Noradrenergic tone mediates marble burying behavior after chronic stress and ethanol.

Carolina R den HartogKatrina L BlandinoMcKenzie L NashEmily R SjogrenMichael A GrampetroDavid E MoormanElena M Vazey

Published in: Psychopharmacology (2020)

These data indicate that NE contributes to the development of anxiety following a history of alcohol and/or stress, and that the influence of both treatment history and NE signaling is sex dependent. These results argue for further investigation of the NE system in relation to disrupted behavior following chronic alcohol and stress, and support the assertion that treatments may differ across sex based on differential neural system engagement.

Keyphrases

stress induced
social media
big data
deep learning
combination therapy
replacement therapy
smoking cessation