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Naked mole rat ovaries allow investigation of ovarian reserve, in vitro germ cell expansion, and oocyte in vitro maturation within a single sample.

Gretchen M RosadoAna Martinez-MarchalMariela Faykoo-MartinezMelissa M HolmesMiguel Angel Brieño-Enríquez
Published in: Reproduction (Cambridge, England) (2024)
Recently, we described that in the naked mole rat ovary it is possible to study the ovarian reserve and the mitotic expansion of the germ cell postnatally. Herein, we show oocyte in vitro maturation and in vitro germ cell expansion using the same ovary.
Keyphrases
  • germ cell
  • oxidative stress
  • cell cycle
  • cell proliferation