S6 ribosomal protein phosphorylation is associated with malignancy of intraductal papillary mucinous neoplasm of the pancreas.

Teijiro HirashitaYuka HirashitaYukio IwashitaYuichi EndoMaki KiyonagaShunro MatsumotoNaoki HijiyaMasatsugu MoriyamaKazunari MurakamiMasafumi Inomata

Published in: Annals of gastroenterological surgery (2020)

S6 phosphorylation was associated with glucose uptake and malignancy of IPMN. Moreover, glucose uptake increased in malignant cells of IPMN, and FDG-PET is useful for detecting malignancy of IPMN.

Keyphrases

pet ct
induced apoptosis
low grade
positron emission tomography
pet imaging
blood glucose
protein kinase
computed tomography
cell cycle arrest
endoplasmic reticulum stress
metabolic syndrome
signaling pathway
oxidative stress
high grade
binding protein
skeletal muscle
insulin resistance
glycemic control