Self-rated health, quality of life and appetite as predictors of initiation of dialysis and mortality in patients with chronic kidney disease stages 4-5: a prospective cohort study.
Birgith Engelst GroveLiv Marit SchougaardNiels Henrik HjollundPer IvarsenPublished in: BMC research notes (2018)
A total of 126 patients with chronic kidney disease with an eGFR of ≤ 25 mL/min/1.73 m2 were followed for a median of 321 (range 10-523) days. Poor appetite was associated with mortality (hazard ratio 20.9, 95% CI 3.7-129.8). Initiation of dialysis was associated with low self-rated health (hazard ratio 5.2, 95% CI 1.2-24.0). Mean decline in estimated glomerular filtration rate was - 0.9 mL/min/1.73 m2 (95% CI - 1.6 to - 0.2). Decline in self-rated health (p = 0.001) and appetite (p = 0.002) were correlated with reduction in renal function.
Keyphrases
- public health
- healthcare
- mental health
- weight loss
- chronic kidney disease
- health information
- small cell lung cancer
- cardiovascular events
- body weight
- end stage renal disease
- risk factors
- health promotion
- epidermal growth factor receptor
- coronary artery disease
- cardiovascular disease
- tyrosine kinase
- risk assessment
- peritoneal dialysis