Systematic analyses reveal long non-coding RNA (PTAF)-mediated promotion of EMT and invasion-metastasis in serous ovarian cancer.

Haihai LiangXiaoguang ZhaoChengyu WangJian SunYingzhun ChenGuoyuan WangLei FangRui YangMengxue YuYunyan GuHongli Shan

Published in: Molecular cancer (2018)

The lncRNA PTAF, a mediator of TGF-β signaling, can predispose OvCa patients to metastases and may serve as a potential target for anti-metastatic therapies for mesenchymal OvCa patients.

Keyphrases

long non coding rna
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
stem cells
peritoneal dialysis
prognostic factors
squamous cell carcinoma
epithelial mesenchymal transition
high grade
risk assessment
climate change
genome wide
transforming growth factor