Immunotherapeutic role of cabazitaxel treatment in the activation of TLR3 signalling in metastatic castration-resistant prostate cancer in vitro.

Asuman Deveci Ozkan Gamze Guney Eskiler Suleyman Kaleli Elvan Sahin

Published in: Molecular biology reports (2021)

Co-treatment of CAB and Poly I:C was more effective in mCRPC cells with less toxicity in control cells. However, further investigations are required to elucidate the molecular mechanisms of TLRs signalling upon CAB treatment at the molecular level to further validate the immunotherapeutic efficacy of CAB in mCRPC.

Keyphrases

induced apoptosis
squamous cell carcinoma
small cell lung cancer
cell cycle arrest
oxidative stress
toll like receptor
cell death
cell proliferation
single molecule