Osteopontin and fibronectin in lung tissue, serum, and bronchoalveolar lavage fluid of dogs with idiopathic pulmonary fibrosis and control dogs.
Aline FastresElodie RoelsAlexandru Cosmin TutunaruGéraldine BolenAnne-Christine MerveilleMichael J DayMutien-Marie GariglianiNadine AntoineCécile ClercxPublished in: Journal of veterinary internal medicine (2023)
Results suggest that SPP1 is involved in pathogenesis of IPF and could predispose that breed to the disease. Osteopontin serum concentration could serve as a diagnostic biomarker of IPF.