Polyclonal Dissemination of NDM-1- and NDM-9-Producing Escherichia coli and Klebsiella pneumoniae in French Polynesia.
Saoussen OueslatiCécile EmeraudVictor GrosperrinMarc LevyGarance CotellonElodie CretonLauraine GauthierRémy A BonninThierry NaasLaurent DortetPublished in: Antimicrobial agents and chemotherapy (2021)
The whole-genome sequencing analysis revealed a polyclonal dissemination of NDM-1 and NDM-9 variants in Escherichia coli (n = 20) and Klebsiella pneumoniae (n = 2) in Tahiti since 2015 via interspecies transfer of three different bla NDM-carrying plasmids (IncR, IncHI2, and IncF) and patient-to-patient cross-transmission. It highlights the potential risk of importation of NDM producers in France, where French Polynesia is not considered stricto sensu a foreign country from which repatriated patients have to be screened.
Keyphrases
- klebsiella pneumoniae
- escherichia coli
- multidrug resistant
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- single cell
- peritoneal dialysis
- biofilm formation
- gene expression
- dna methylation
- cystic fibrosis
- risk assessment
- pseudomonas aeruginosa
- genome wide
- staphylococcus aureus
- human health