Conjugated Bile Acids Accelerate Progression of Pancreatic Cancer Metastasis via S1PR2 Signaling in Cholestasis.

Joy SarkarHiroaki AokiRongrong WuMasayo AokiPhillip HylemonHuiping ZhouKazuaki Takabe

Published in: Annals of surgical oncology (2022)

CBAs accelerated growth of S1PR2 predominant PC both in vitro and in vivo. This finding implicates S1PR2 as a potential therapeutic target in metastatic S1PR2 predominant pancreatic cancer.

Keyphrases

squamous cell carcinoma
small cell lung cancer
photodynamic therapy
risk assessment