Metal-Free, Initiator-Free Graphene Oxide-Catalyzed Trifluoromethylation of Arenes.
Jingyu ZhangYun YangJingxian FangGuo-Jun DengHang GongPublished in: Chemistry, an Asian journal (2017)
The direct C-H trifluoromethylation of arenes catalyzed by graphene oxide (GO) under safe conditions is described. This strategy is metal-free, initiator-free, safe, and scalable. It employs a readily available CF3 source and the reaction can be easily controlled to obtain a mono-trifluorinated product. This method opens a new avenue for GO-catalyzed chemistry.