Bioinformatics and systems-biology approach to identify common pathogenic mechanisms for COVID-19 and systemic lupus erythematosus.

Yinlan WuYanhong LiYu ZhouXiufeng BaiYi Liu

Published in: Autoimmunity (2024)

COVID-19 and SLE patients share many common hub genes, related pathways and regulatory networks. Based on these common targets, we found many potential drugs that could be used in treating patient with COVID-19 or COVID-19 combined with SLE.

Keyphrases

coronavirus disease
systemic lupus erythematosus
sars cov
disease activity
end stage renal disease
respiratory syndrome coronavirus
chronic kidney disease
ejection fraction
newly diagnosed
prognostic factors
rheumatoid arthritis
genome wide
gene expression
bioinformatics analysis
network analysis
human health