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Effect of concentration, temperature, and time on the stability of hepatitis C virus nucleic acid in serum.

Ya-Pei WangShu-Wen YangFan JiaWei WangXue XuYi-Xuan WangJing-Feng BiBo-An Li
Published in: Microbiology spectrum (2024)
Previously, there were few reports about the influence of different concentrations of sample nucleic acid on the stability of samples at various temperatures and times in various literatures. Therefore, it is necessary to analyze the influence of concentration factors on the stability of samples and test results at different storage times and temperatures. This study took the concentration of hepatitis C virus nucleic acid as the research object to further understand the stability of hepatitis C virus nucleic acid test samples under various storage conditions, to provide data reference for the treatment of hepatitis C virus nucleic acid and RNA test samples before clinical laboratory test, and provide guidance and help for the improvement of laboratory quality control.
Keyphrases
  • nucleic acid
  • hepatitis c virus
  • human immunodeficiency virus
  • quality control
  • machine learning
  • deep learning
  • hiv infected
  • adverse drug
  • antiretroviral therapy
  • drug induced