HDAC3 inhibition protects against peripheral and central alterations in an animal model of obesity.

Franciéle Romero MachadoSilvana Peterini BoeiraVandreza Cardoso BortolottoStífani Machado AraujoMárcia Rósula PoetiniCristini Escobar VianaMarina PrigolLeandro Cattelan SouzaMarcelo Gomes De Gomes

Published in: Pharmacological reports : PR (2023)

Therefore, HDAC3 inhibition can represent a promising pharmacological target for the treatment of obesity.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
histone deacetylase
skeletal muscle
body mass index
chemotherapy induced