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Case report: Comprehensive management of painful diabetic neuropathy-Addressing opioid-induced hyperalgesia through multimodal approaches.

Robert MaksymowiczCyprian N StrączekJeremi J MatysekDominika M LechKrzysztof Nosek
Published in: Medicine (2024)
Effective management of OIH involves gradual opioid tapering and a multimodal therapeutic approach. However, the optimal treatment strategies and the frequency of OIH occurrence remain areas of uncertainty, relying heavily on clinical expertise and individualized patient care. Further research is needed to refine these treatment strategies and improve patient outcomes.
Keyphrases
  • pain management
  • case report
  • chronic pain
  • type diabetes
  • risk assessment
  • high glucose
  • diabetic rats
  • neuropathic pain
  • spinal cord
  • oxidative stress
  • endothelial cells
  • stress induced