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Effects of finerenone in persons with CKD and T2D are independent of HbA1c at baseline, HbA1c variability, diabetes duration and insulin use at baseline.

Janet B McGillRajiv AgarwalStefan D AnkerGeorge L BakrisGerasimos FilippatosBertram PittLuis M RuilopeAndreas L BirkenfeldM Luiza CaramoriMeike BrinkerAmer JosephAndrea LageRobert LawatscheckCharlie ScottEllen Burgessnull null
Published in: Diabetes, obesity & metabolism (2023)
Finerenone efficacy was not modified by baseline HbA1c, HbA1c variability, diabetes duration or baseline insulin use. Greater HbA1c variability appeared to be associated with increased risk of cardiorenal outcomes. This article is protected by copyright. All rights reserved.
Keyphrases
  • type diabetes
  • glycemic control
  • cardiovascular disease
  • chronic kidney disease
  • insulin resistance
  • adipose tissue
  • skeletal muscle