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In Vitro Low-Bortezomib Doses Induce Apoptosis and Independently Decrease the Activities of Glutathione S-Transferase and Glutathione Peroxidase in Multiple Myeloma, Taking into Account the GSTT1 and GSTM1 Gene Variants.

Szymon ZmorzyńskiSylwia Popek-MarciniecBeata BiernackaAneta Szudy-SzczyrekSylwia ChocholskaWojciech StykJoanna Czerwik-MarcinkowskaGrazyna Swiderska-Kolacz
Published in: Genes (2024)
variants but only at some bortezomib doses.
Keyphrases
  • multiple myeloma
  • copy number
  • oxidative stress
  • genome wide
  • endoplasmic reticulum stress
  • hydrogen peroxide
  • cell death
  • cell cycle arrest
  • nitric oxide
  • cell proliferation
  • genome wide identification