Increasing risk of mortality across the spectrum of aortic stenosis is independent of comorbidity & treatment: An international, parallel cohort study of 248,464 patients.
Jordan B StromDavid PlayfordSimon StewartStephanie LiChangyu ShenJiaman XuGeoffrey A StrangePublished in: PloS one (2022)
The findings of this study suggest that patients with moderate AS have a potential increased risk of death and cardiovascular mortality, regardless of age, sex, and LVEF. Hence, these data suggest the need to develop specific strategies to detect and treat individuals with moderate AS.
Keyphrases
- ejection fraction
- aortic stenosis
- end stage renal disease
- transcatheter aortic valve replacement
- aortic valve replacement
- transcatheter aortic valve implantation
- cardiovascular events
- aortic valve
- left ventricular
- newly diagnosed
- high intensity
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- risk factors
- electronic health record
- type diabetes
- coronary artery disease
- patient reported outcomes
- atrial fibrillation
- deep learning