A systematic assessment of the characteristics of randomised controlled trials cited by acute coronary syndrome clinical practice guidelines.
Maribel Gonzalez-Del-HoyoCaterina Mas-LladoJoan Siquier-PadillaLaura Blaya-PeñaJ J CoughlanVicente PeralXavier RosselloPublished in: European heart journal. Quality of care & clinical outcomes (2023)
This analysis demonstrates that RCTs cited by CPGs can still have significant methodological issues and limitations, highlighting that a better understanding of the methodological aspects of RCTs is crucial in order to formulate recommendations relevant to clinical practice.