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Association of Tumor PD-L1 Expression with the T790M Mutation and Progression-Free Survival in Patients with EGFR-Mutant Non-Small Cell Lung Cancer Receiving EGFR-TKI Therapy.

Minehiko InomataKenji AzechiNaoki TakataKana HayashiKotaro TokuiChihiro TakaSeisuke OkazawaKenta KambaraShingo ImanishiToshiro MiwaRyuji HayashiShoko MatsuiKazuyuki Tobe
Published in: Diagnostics (Basel, Switzerland) (2020)
Patients with negative tumor PD-L1 expression showed longer PFS and a higher proportion of acquisition of T790M mutation of EGFR after first-line treatment with an EGFR-TKI.
Keyphrases
  • tyrosine kinase
  • epidermal growth factor receptor
  • small cell lung cancer
  • free survival
  • advanced non small cell lung cancer
  • chronic myeloid leukemia
  • cell therapy
  • replacement therapy