Orientia tsutsugamushi modulates cellular levels of NF-κB inhibitor p105.
Tanaporn WangsanutKatelynn R BrannHaley E AdcoxJason A CarlyonPublished in: PLoS neglected tropical diseases (2021)
O. tsutsugamushi specifically stabilizes p105 to inhibit the canonical NF-κB pathway, which advances understanding of how it counters host immunity to establish infection.