Transcranial Doppler screening in Nigerian children with sickle cell disease: A 10-year longitudinal study on the SPPIBA cohort.
IkeOluwa A LagunjuAdeyemi LabaekaJoy N IbehAdebola E OrimadegunBiobele Jotham BrownOlugbemiro O SodeindePublished in: Pediatric blood & cancer (2021)
The majority of Nigerian children with SCD and elevated TCD velocities achieved significant decline in TAMMV within the first year of HU therapy but on higher doses of HU. It might be important to individualise HU doses for optimal outcomes in primary stroke prevention.