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Explaining decisions of graph convolutional neural networks: patient-specific molecular subnetworks responsible for metastasis prediction in breast cancer.

Hryhorii CheredaAnnalen BleckmannKerstin MenckJúlia Perera-BelPhilip StegmaierFlorian AuerFrank KramerAndreas LehaTim Beißbarth
Published in: Genome medicine (2021)
The developed method could be potentially highly useful on interpreting classification results in the context of different omics data and prior knowledge molecular networks on the individual patient level, as for example in precision medicine approaches or a molecular tumor board.
Keyphrases
  • convolutional neural network
  • deep learning
  • healthcare
  • machine learning
  • case report
  • electronic health record
  • single cell
  • big data
  • young adults