Effect of Solution pH on the Biomechanics of Intact Cornea From Inflation Tests.

The study demonstrated that the PBS drops of various pH administration could decrease the corneal stiffness independent of corneal swelling. Following the PBS administration, the stiffness changes were more prominent as the posterior pressure increased, and the minimal effect was achieved with slightly acidic PBS. The research provides the essence for stabilizing the corneal biomechanical properties by regulating the pH value of tear film and intraocular pressure.