Cannabinoid Receptor Agonist WIN55, 212-2 Attenuates Injury in the Hippocampus of Rats after Deep Hypothermic Circulatory Arrest.

Ming-Huan YuQin YangYou-Peng ZhangJia-Hui WangRen-Jian-Zhi ZhangZhi-Gang LiuXiao-Cheng Liu

Published in: Brain sciences (2023)

the administration of WIN55, 212-2 alleviates hippocampal injury induced by DHCA in rats by regulating intrinsic inflammatory and oxidative stress responses through a CB1R-dependent mechanism.

Keyphrases

cerebral ischemia
oxidative stress
extracorporeal membrane oxygenation
cell cycle
cell proliferation
mouse model
cognitive impairment
brain injury