Development of a risk classification system combining TN-categories and circulating EBV DNA for non-metastatic NPC in 10,149 endemic cases.

Fo-Ping ChenLi LinJin-Hui LiangSze Huey TanEnya H W OngYing-Shan LuoLuo HuangAdelene Y L SimHai-Tao WangTian-Sheng GaoBin DengGuan-Qun ZhouJia KouMatthew Chin Heng ChuaYing Sun

Published in: Therapeutic advances in medical oncology (2021)

Herein, we developed and validated a risk classification system that combines the AJCC/UICC 8th edition TN-stage classification and cfEBV DNA for non-metastatic NPC. Our new clinicomolecular model provides improved OS prediction over the current staging system.

Keyphrases

squamous cell carcinoma
small cell lung cancer
circulating tumor
single molecule
cell free
machine learning
lymph node
deep learning