Genetic features associated with 18F-FDG uptake in intrahepatic cholangiocarcinoma.

Keun Soo AhnKoo Jeong KangYong Hoon KimTae-Seok KimBong-Il SongHae Won KimDaniel O'BrienLewis R RobertsJeong Woo LeeKyoung Sook Won

Published in: Annals of surgical treatment and research (2019)

The genomic features of gene expression and pathways can be predicted by FDG uptake features in iCCA. Patients with high FDG uptake have enriched cell cycle, metabolism and hypoxic pathways, which may lead to a more rational targeted treatment approach.

Keyphrases

cell cycle
pet ct
gene expression
pet imaging
positron emission tomography
cell proliferation
copy number
dna methylation
computed tomography
genome wide