DNA methylation is associated with inhaled corticosteroid response in persistent childhood asthmatics.

Alberta L WangOlena GruzievaWeiliang QiuSimon Kebede MeridJuan C CeledónBenjamin A RabyCilla SöderhällDawn L DeMeoScott T WeissErik MelénKelan G Tantisira

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2019)

Differential DNA methylation of IL12B and CORT are associated with inhaled corticosteroid treatment response in persistent childhood asthmatics. Pharmaco-methylation can identify novel markers of treatment sensitivity in asthma.

Keyphrases

dna methylation
genome wide
gene expression
cystic fibrosis
chronic obstructive pulmonary disease
early life
lung function
copy number
combination therapy
replacement therapy
smoking cessation