Premorbid Steatohepatitis Increases the Seriousness of Dextran Sulfate Sodium-induced Ulcerative Colitis in Mice.

Meng-Yu WangZi-Xuan WangLei-Jie HuangRui-Xu YangZi-Yuan ZouWen-Song GeTian-Yi Ren Jian-Gao Fan

Published in: Journal of clinical and translational hepatology (2022)

Premorbid steatohepatitis significantly aggravated DSS-induced colitis and brought about a lethal phenotype. Potential links between NASH and UC pathogeneses can be investigated using this model.

Keyphrases

ulcerative colitis
high glucose
diabetic rats
liver fibrosis
drug induced
atomic force microscopy
human health
type diabetes
endothelial cells
risk assessment
climate change
adipose tissue
stress induced