Epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. A case report.
Ashraf S GorgeyTommy W SutorJacob A GoldsmithAreej N EnnasrTimothy D LavisDavid X CifuRobert TrainerPublished in: Annals of clinical and translational neurology (2022)
A male with C7 complete tetraplegia participated in 14 weeks of body weight supported treadmill training (BWSTT) combined with spinal cord epidural stimulation (SCES), 4 weeks of no intervention, and two more weeks of BWSTT + SCES. The participant presented with unstable resting seated blood pressure (BP; 131/66 mmHg). After retrospective analysis, resting systolic BP decreased and diastolic BP increased, yielding a safe mean arterial BP. There was a fivefold increase in BWSTT bouts per session, and percentage of body weight support decreased to 69%. BWSTT + SCES safely and effectively regulated resting BP and mitigated symptoms of orthostatic intolerance. These effects were not maintained after 4 weeks without training.
Keyphrases
- body weight
- blood pressure
- heart rate
- spinal cord
- heart rate variability
- hypertensive patients
- gestational age
- spinal cord injury
- left ventricular
- virtual reality
- heart failure
- neuropathic pain
- high intensity
- transcription factor
- mouse model
- metabolic syndrome
- ejection fraction
- type diabetes
- preterm birth
- sleep quality
- skeletal muscle
- working memory
- adipose tissue