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The Drosophila hematopoietic niche assembles through collective cell migration controlled by neighbor tissues and Slit-Robo signaling.

Kara A NelsonKari F LenhartLauren AnlloStephen DiNardo
Published in: bioRxiv : the preprint server for biology (2024)
A ne w example of niche formation is provided which reveals the mode of niche cell migration, implicates extrinsic sources that deliver positional information, and uncovers the signaling pathway required for the precise, stereotypical positioning of the niche.
Keyphrases
  • cell migration
  • signaling pathway
  • gene expression
  • bone marrow
  • pi k akt
  • epithelial mesenchymal transition
  • drinking water
  • health information
  • cell proliferation