The pivotal role of timing of intravenous thrombolysis bridging treatment prior to endovascular thrombectomy.
Jeremy MoladHen HalleviEstelle SeymanEinor Ben-AssayagTali Jonas-KimchiUdi SadehOfer RotschildNaaem SimaanAnat HorevJose CohenRonen R LekerAsaf HonigPublished in: Therapeutic advances in neurological disorders (2023)
In this study, we found OTD times to have a significant effect on the impact of IVT bridging treatment. Our study shows that among patients with OTD < 2 h bridging treatment may be associated with higher rates of successful recanalization. By contrast, in patients with OTD > 2 h, bridging treatment was associated with worse outcomes. Further time-sensitive randomized trials are needed.