Dysbiosis in the oral microbiomes of anti-CCP positive individuals at risk of developing rheumatoid arthritis.
Zijian ChengThuy DoKulveer MankiaJosephine MeadeLaura HuntVal ClerehughAlastair SpeirsAradhna TugnaitPaul EmeryDeirdre Ann DevinePublished in: Annals of the rheumatic diseases (2020)
Anti-CCP positive at-risk individuals have dysbiotic subgingival microbiomes and increased abundance of P. gingivalis compared with controls. This supports the hypothesis that the oral microbiome and specifically P. gingivalis are important in RA initiation.