Sensory nerve degeneration in a mouse model mimicking early manifestations of familial amyloid polyneuropathy due to transthyretin Ala97Ser.
Hung-Wei KanH ChiangW-M LinI-S YuS-W LinS-T HsiehPublished in: Neuropathology and applied neurobiology (2018)
These results demonstrate that the hTTRA97S mouse model develops sensory nerve pathology and corresponding physiology mimicking A97S-FAP and provides a platform to develop new therapies for the early stage of A97S-FAP.