Microstructural plasticity in nociceptive pathways after spinal cord injury.

Sreenath P KyathanahallyMichela AzzaritoJan RosnerVince D CalhounClaudia BlaiottaJohn AshburnerNikolaus WeiskopfKatja WiechKarl FristonGabriel ZieglerPatrick Freund

Published in: Journal of neurology, neurosurgery, and psychiatry (2021)

The degree of microstructural changes across ascending and descending nociceptive pathways is critically implicated in the maintenance of NP. Tracking maladaptive plasticity unravels the intimate relationships between neurodegenerative and compensatory processes in NP states and may facilitate patient monitoring during therapeutic trials related to pain and neuroregeneration.

Keyphrases

neuropathic pain
white matter
chronic pain
spinal cord
spinal cord injury
case report
pain management
pulmonary artery
multiple sclerosis
coronary artery
aortic dissection