Moderate correlation between systemic IL-6 responses and CRP with trough concentrations of voriconazole.

Bas VreugdenhilWalter J F M van der VeldenTon FeuthMatthijs KoxPeter PickkersFrank L van de VeerdonkNicole M A BlijlevensRoger J M Brüggemann

Published in: British journal of clinical pharmacology (2018)

VCZ trough concentrations correlate with IL-6, IL-8 and CRP levels but only moderately explain the variability in VCZ pharmacokinetics. Future prospective studies should be undertaken to confirm these findings, and incorporate the data obtained into pharmacokinetic models, to refine the predictive behaviour.

Keyphrases

electronic health record
big data
current status
machine learning
deep learning
drug induced