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TERT Promoter Mutation Analysis for Blood-Based Diagnosis and Monitoring of Gliomas.

Koushik MuralidharanAnudeep YekulaJulia L SmallZachary S RoshKeiko M KangLan WangSpencer LauHui ZhangHakho LeeChetan BettegowdaMichael R ChicoineSteven N KalkanisGanesh M ShankarBrian Vala NahedWilliam T CurryPamela S JonesDaniel P CahillLeonora BalajBob S Carter
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Our results demonstrate the feasibility of detecting circulating cfDNA TERT promoter mutations in patients with glioma with clinically relevant sensitivity and specificity.
Keyphrases
  • dna methylation
  • transcription factor
  • gene expression
  • high grade