Dual Biologic or Small Molecule Therapy in Refractory Pediatric Inflammatory Bowel Disease (DOUBLE-PIBD): A Multicenter Study from the Pediatric IBD Porto Group of ESPGHAN.
Anat Yerushalmy-FelerChristine OlbjornKaija-Leena KolhoMarina AloiFrancesca MustoJavier Martin-de-CarpiAna Lozano-RufDotan YogevManar MatarLuca ScaralloMatteo BramuzzoLissy de RidderBen KangChristoph NordenDavid C WilsonChristos TzivinikosDan TurnerShlomi CohenPublished in: Inflammatory bowel diseases (2023)
Dual biologic therapy may be effective in children with refractory IBD. The potential efficacy should be weighed against the risk of serious adverse events.