Duloxetine for the Prevention of Oxaliplatin Induced Peripheral Neuropathy: A Randomized, Placebo-Controlled, Double-blind Clinical Trial.
Mahdi AghiliNima Mousavi DarzikolaeeMohammad BabaeiReza GhalehtakiFarshid FarhanSeyede Zahra Emami RazaviSaeed RezaeiEbrahim EsmatiFarhad SamieiMohaddeseh AzadvariBorna FarazmandReyhaneh BayaniArdavan AmiriPublished in: Journal of gastrointestinal cancer (2022)
Although a definite conclusion might be difficult to draw but administering duloxetine for 14 days in each chemotherapy cycle could not decrease the incidence of acute OIPN based on CTCAE grading system.