Giemsa-stained pseudo-micronuclei in rat skin treated with vitamin D3 analog, pefcalcitol.

Akira TakeiriKenji TanakaAsako HaradaKaori MatsuzakiMariko YanoShigeki MotoyamaChie KatohMasayuki Mishima

Published in: Genes and environment : the official journal of the Japanese Environmental Mutagen Society (2017)

Pefcalcitol was concluded to be negative in the rat skin MN test. The present study demonstrated that Giemsa staining gave a misleading positive result in the skin MN test, because Giemsa stained keratohyalin granules.

Keyphrases

soft tissue
wound healing
oxidative stress
room temperature
metal organic framework
newly diagnosed
ionic liquid