Genetic sequence characterization and naturally acquired immune response to Plasmodium vivax Rhoptry Neck Protein 2 (PvRON2).
Najara C BittencourtJuliana A LeiteAna Beatriz I E SilvaTamirys S PimentaJoão Luiz Silva-FilhoGustavo C CassianoStefanie C P LopesJoao C K Dos-SantosCatarina BourgardHelder I NakayaAna Maria Revorêdo da Silva VenturaMarcus V G LacerdaMarcelo U FerreiraRicardo L D MachadoLetusa AlbrechtFabio Trindade Maranhão CostaPublished in: Malaria journal (2018)
PvRON2 was conserved among the studied isolates. The presence of naturally acquired antibodies to this protein in the absence of the disease suggests that PvRON2 induces a long-term antibody response. These results indicate that PvRON2 is a potential malaria vaccine candidate.