Bleeding phenotype according to factor level in 825 children with nonsevere hemophilia: data from the PedNet cohort.
Marloes S de KovelCarmen Escuriola-EttingshausenChristoph KönigsSusanna RantaKathelijn Fischernull null
Published in: Journal of thrombosis and haemostasis : JTH (2024)
Endogenous factor activity of >5% was identified as a threshold to significantly lower joint bleeding rate, while FVIII levels >15% and FIX levels >10% were sufficient to achieve the goal of 0 bleeds in this pediatric cohort.