Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinoma.

Robert C GrantRobert DenrocheGun Ho JangKlaudia M NowakAmy ZhangAyelet BorgidaSpring HolterJames T TophamJulie WilsonAnna DoddRaymond JangRebecca PrinceJoanna M KarasinskaDavid F SchaefferYifan WangGeorge ZogopoulosScott BerryDiane SimeoneDaniel J RenoufFaiyaz NottaGrainne O'KaneJennifer KnoxSandra FischerSteven Gallinger

Published in: Gut (2020)

MMRD pancreatic cancers have distinct clinical, pathological and genomic profiles. Patients with MMRD pancreatic cancer should be considered for basket trials targeting enhanced immunogenicity or the unique genomic drivers in these malignancies.

Keyphrases

copy number
young adults
drug delivery