Long-term response to pimitespib in postoperative recurrent gastrointestinal stromal tumors with PDGFRA D842V mutation: a case report.

Ryugo TeranishiTsuyoshi TakahashiYukinori KurokawaTakuro SaitoKazuyoshi YamamotoKotaro YamashitaKoji TanakaTomoki MakinoKiyokazu NakajimaHidetoshi EguchiYuichiro Doki

Published in: Surgical case reports (2023)

We report the first case of long-term response to PIMI in PDGFRA D842V mutant GIST. Pimitespib may be effective for treating GIST harboring this mutation by inhibiting HSP90.

Keyphrases

patients undergoing
heat shock protein
signaling pathway
heat stress