Skeletal muscle symptoms and quantitative MRI in females with dystrophinopathy.

Breana M JenkinsLathan D DixonKevin J KokeshCarla D ZingarielloKrista VandenborneGlenn A WalterAlison M Barnard

Published in: Muscle & nerve (2024)

Symptomatic females with dystrophinopathy quantitatively demonstrate muscle replacement by fat and inflammation, along with impairments in functional ability and cardiac function. Additional research is needed to evaluate how symptoms and muscle involvement change longitudinally.

Keyphrases

skeletal muscle
insulin resistance
oxidative stress
adipose tissue
sleep quality
magnetic resonance imaging
contrast enhanced
high resolution
diffusion weighted imaging
physical activity