Risk of post-acute sequelae of SARS-CoV-2 infection associated with pre-coronavirus disease obstructive sleep apnea diagnoses: an electronic health record-based analysis from the RECOVER initiative.
Hannah L MandelGunnar ColleenSajjad AbedianNariman AmmarL Charles BaileyTellen D BennettM Daniel BrannockShari B BrosnahanYu ChenChristopher G ChuteJasmin DiversMichael D EvansMelissa HaendelMargaret A HallKathryn HirabayashiMady HornigStuart D KatzAna C KriegerJohanna LoombaVitaly LormanDiego R MazzottiJulie McMurryRichard A MoffittNathan M PajorEmily Rose PfaffJeff RadwellHanieh RazzaghiSusan RedlineElle SeibertAnisha SekarSuchetha SharmaTanayott ThaweethaiMark G WeinerYun Jae YooAndrea ZhouLorna E ThorpePublished in: Sleep (2023)
Adults with preexisting OSA were found to have significantly elevated odds of probable PASC. This finding was consistent across data sources, approaches for identifying COVID-19-positive patients, and definitions of PASC. Patients with OSA may be at elevated risk for PASC after SARS-CoV-2 infection and should be monitored for post-acute sequelae.
Keyphrases
- electronic health record
- obstructive sleep apnea
- coronavirus disease
- respiratory syndrome coronavirus
- liver failure
- positive airway pressure
- end stage renal disease
- sars cov
- respiratory failure
- chronic kidney disease
- ejection fraction
- newly diagnosed
- clinical decision support
- drug induced
- adverse drug
- prognostic factors
- quality improvement
- extracorporeal membrane oxygenation
- data analysis