Jianwei Shoutai Pills alleviates miscarriage by modulating gut microbial production of BAs and NLRP3-inflammasome at the maternal-fetal interface of rats.

Si ChenXiaomeng XueHuimin ZhangXuge HuangXinyi LinJiaxin HeLizhu ChenSongping LuoJie Gao

Published in: Phytomedicine : international journal of phytotherapy and phytopharmacology (2024)

JWP restored abnormal activation of the NLRP3-inflammasome in an RU486-induced miscarriage rat model, and corrected the BA disorder by regulating imbalance of the GM.

Keyphrases

nlrp inflammasome
high glucose
diabetic rats
microbial community
signaling pathway
birth weight
drug induced
pregnancy outcomes
mouse model
oxidative stress
pregnant women
energy transfer
quantum dots
stress induced