Occurrence of Diabetic Nephropathy After Renal Transplantation Despite Intensive Glycemic Control: An Observational Cohort Study.
Maarten CoemansElisabet Van LoonEvelyne LerutPieter GillardBen SprangersAleksandar SenevMarie-Paule EmondsJan Van KeerJasper CallemeynLiesbeth DaniëlsJeroen SichienGeert VerbekeDirk KuypersChantal MathieuMaarten NaesensPublished in: Diabetes care (2019)
Mesangial matrix expansion, an early indicator of diabetic nephropathy, can occur rapidly in patients with diabetes before transplantation, despite intensive glycemic control. Prevention of diabetic nephropathy requires more than pursuing low levels of glycated hemoglobin.