Secondary deficiency of neuraminidase 1 contributes to CNS pathology in neurological mucopolysaccharidoses via hypersialylation of brain glycoproteins.

TianMeng XuRachel Heon-RobertsTravis MoorePatricia DubotXuefang PanTianlin GuoChristopher W CairoRebecca HolleyBrian BiggerThomas Martin DurcanThierry LevadeJerôme AusseilBénédicte AmilhonAlexei GorelikBhushan NagarLuisa SturialeAngelo PalmigianoIris RöckleHauke ThieslerHerbert HildebrandtDomenico GarozzoAlexey V Pshezhetsky

Published in: bioRxiv : the preprint server for biology (2024)

Keyphrases

cerebral ischemia
blood brain barrier
resting state
white matter
functional connectivity
replacement therapy
subarachnoid hemorrhage
brain injury