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Secondary deficiency of neuraminidase 1 contributes to CNS pathology in neurological mucopolysaccharidoses via hypersialylation of brain glycoproteins.

TianMeng XuRachel Heon-RobertsTravis MoorePatricia DubotXuefang PanTianlin GuoChristopher W CairoRebecca HolleyBrian BiggerThomas Martin DurcanThierry LevadeJerôme AusseilBénédicte AmilhonAlexei GorelikBhushan NagarLuisa SturialeAngelo PalmigianoIris RöckleHauke ThieslerHerbert HildebrandtDomenico GarozzoAlexey V Pshezhetsky
Published in: bioRxiv : the preprint server for biology (2024)
Keyphrases
  • cerebral ischemia
  • blood brain barrier
  • resting state
  • white matter
  • functional connectivity
  • replacement therapy
  • subarachnoid hemorrhage
  • brain injury