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Determination of lamotrigine in human plasma by HPLC-PDA. Application to forensic samples.

Ines Sánchez-SelleroIván Alvarez-FreirePamela CabarcosLidia Janza-CandalMaría Jesús Tabernero-DuqueAna María Bermejo-Barrera
Published in: Forensic science, medicine, and pathology (2024)
A new HPLC method for the determination of lamotrigine in human plasma was developed and validated. A liquid-liquid extraction using small volumes of buffer and ethylacetate was optimized. The proposed method is suitable for forensic toxicological analysis.
Keyphrases
  • solid phase extraction
  • ms ms
  • simultaneous determination
  • high performance liquid chromatography
  • molecularly imprinted
  • tandem mass spectrometry
  • liquid chromatography
  • mass spectrometry