Login / Signup

Synchronicity of genetic variants between primary sites and metastatic lymph nodes, and prognostic impact in nodal metastatic lung adenocarcinoma.

Masaoki ItoYoshihiro MiyataShoko HiranoShingo KimuraFumiko IrisunaKyoko IkedaKei KushitaniNaoto KishiYasuhiro TsutaniYukio TakeshimaMorihito Okada
Published in: Journal of cancer research and clinical oncology (2019)
Cases harbouring targetable genetic variants had a higher risk of recurrence, but PRS was prolonged by TKI therapy. Classification according to the targetable genetic status provides a basis for predicting recurrence and determining treatment strategies after recurrence.
Keyphrases
  • lymph node
  • free survival
  • squamous cell carcinoma
  • small cell lung cancer
  • tyrosine kinase
  • genome wide
  • gene expression
  • advanced non small cell lung cancer
  • dna methylation
  • rectal cancer